Description

α-(4-Chlorophenyl)-2-Ethyl-1,3-Dioxolane-2-Acetonitrile is a high-purity, versatile chemical intermediate featuring a unique dioxolane-protected acetonitrile functional group. This compound is valued for its role as a critical building block in the synthesis of complex organic molecules, offering a protected form that enhances selectivity in multi-step reactions. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic structures.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides, leveraging the chlorophenyl moiety for biological activity.
• Fine Chemical Production: Serves as a specialized building block for creating complex flavors, fragrances, and advanced material precursors.
• Academic & Industrial R&D: Employed in organic chemistry research for methodology development, catalysis studies, and exploring new reaction pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	α-(4-Chlorophenyl)-2-Ethyl-1,3-Dioxolane-2-Acetonitrile
CAS No.	55474-41-4
Molecular Formula	C₁₃H₁₄ClNO₂
Molecular Weight	251.71 g/mol
Synonyms	2-(4-Chlorophenyl)-2-ethyl-1,3-dioxolane-2-acetonitrile; 2-(4-Chlorophenyl)-2-ethyl-1,3-dioxolane-2-acetonitrile; 4-Chloro-α-(2-ethyl-1,3-dioxolan-2-yl)benzeneacetonitrile; (4-Chlorophenyl)(2-ethyl-1,3-dioxolan-2-yl)acetonitrile; α-(p-Chlorophenyl)-2-ethyl-1,3-dioxolane-2-acetonitrile; 2-Ethyl-2-[(4-chlorophenyl)(cyano)methyl]-1,3-dioxolane
EINECS	Contact for details

Quality Control

Our α-(4-Chlorophenyl)-2-Ethyl-1,3-Dioxolane-2-Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.