Description

L-Tyrosine-13C9 is a stable isotope-labeled analog of the essential amino acid L-Tyrosine, where all nine carbon atoms are replaced with the carbon-13 isotope. This high-purity labeled compound is critical for ensuring accuracy and reliability in advanced quantitative analytical techniques. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic manufacturers requiring precise internal standards for mass spectrometry.

Application

• Used as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate quantification of endogenous L-Tyrosine in complex biological matrices.
• Essential in metabolomics and proteomics research for tracing metabolic pathways, studying protein turnover, and understanding amino acid metabolism disorders.
• Applied in pharmaceutical development and pharmacokinetic (PK) studies to monitor drug metabolism and assess the bioavailability of tyrosine-containing compounds.
• Employed in the production of in vitro diagnostic (IVD) kits and calibrators for clinical assays measuring amino acid levels.
• Facilitates nutritional research focused on protein synthesis, amino acid requirements, and sports science.
• Serves as a labeled precursor in the synthesis of more complex 13C-labeled compounds for specialized research applications.

Basic Information

Product Name	L-Tyrosine-13C9
CAS No.	55443-60-2
Molecular Formula	13C9H11NO3
Molecular Weight	190.14 (based on 13C)
Synonyms	(2S)-2-Amino-3-(4-hydroxyphenyl)propanoic acid-13C9
L-Tyrosine (13C9)
Tyrosine-13C9
TYR-13C9
Y-13C9
(S)-Tyrosine-13C9
4-Hydroxy-L-phenylalanine-13C9
EINECS	Contact for details

Quality Control

Every batch of our L-Tyrosine-13C9 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing performed via NMR, HPLC, and MS. A detailed Certificate of Analysis (COA) is provided with each shipment, reporting specific data for assay, isotopic enrichment, optical rotation, and related substances. Our quality commitment ensures consistency and reliability for your most demanding research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Optical Rotation	-10.0° to -12.0° (c=5 in 1N HCl)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.