Description

n-(2,2,3,3,4,4,4-Heptafluorobutyryl)-L-Ala-L-Phe-Ome is a specialized fluorinated dipeptide derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique properties imparted by the heptafluorobutyryl group, which can enhance metabolic stability, lipophilicity, and bioavailability in target molecules. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly in the creation of protease inhibitors, peptide-based therapeutics, and as a key intermediate for introducing fluorinated motifs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel peptide-based drugs and protease inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to incorporate fluorinated groups, improving drug-like properties.
• Bioconjugation & Probe Synthesis: Serves as a precursor for creating fluorescent or affinity probes for biochemical and diagnostic applications.
• Peptidomimetics Development: Integral in designing and synthesizing stable peptide mimics for therapeutic and research purposes.
• Chemical Biology Tool: Employed to study enzyme mechanisms and protein-protein interactions where fluorinated peptides are required.
• Advanced Material Synthesis: Potential use as a monomer or modifier in creating specialty polymers with unique surface properties.

Basic Information

Product Name	n-(2,2,3,3,4,4,4-Heptafluorobutyryl)-L-Ala-L-Phe-Ome
CAS No.	55401-56-4
Molecular Formula	C18H19F7N2O5
Molecular Weight	476.34 g/mol
Synonyms	Hfb-L-Ala-L-Phe-OMe; L-Alanyl-L-phenylalanine methyl ester, N-(2,2,3,3,4,4,4-heptafluoro-1-oxobutyl)-; Methyl N-(heptafluorobutyryl)-L-alanyl-L-phenylalaninate; Heptafluorobutyryl-Ala-Phe-OMe; N-Heptafluorobutyryl-L-alanyl-L-phenylalanine methyl ester; CAS 55401-56-4; Ala-Phe-OMe, N-Hfb-; Fluorinated Ala-Phe dipeptide derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical intermediates. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific batch results are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider using inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.