Description

Dansylarginine n-(3-Ethyl-1,5-Pentanediyl)Amide is a specialized dansyl-labeled arginine derivative, a key chemical tool in biochemical and pharmaceutical research. Its core value lies in its utility as a fluorescent probe and enzyme substrate, enabling sensitive detection and mechanistic studies. This compound is essential for researchers and developers in proteomics, enzymology, and drug discovery, particularly for investigating protease activity and protein-protein interactions.

Application

• Protease & Enzyme Assays: Acts as a sensitive fluorogenic substrate for studying the kinetics and inhibition of trypsin-like serine proteases.
• Biochemical Research: Used as a model compound in proteomics for understanding protein digestion, peptide mapping, and post-translational modifications.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize novel protease inhibitors as potential therapeutic agents.
• Diagnostic Development: Serves as a key component in developing fluorescent diagnostic kits for detecting specific enzymatic activities linked to diseases.
• Peptide Chemistry & Labeling: Utilized in advanced peptide synthesis as a building block or for introducing a fluorescent dansyl tag onto peptides for tracking and analysis.
• Academic & Institutional Research: A fundamental reagent in university and institutional labs for graduate-level research and method development in biochemistry.

Basic Information

Product Name	Dansylarginine n-(3-Ethyl-1,5-Pentanediyl)Amide
CAS No.	55381-72-1
Molecular Formula	C25H41N7O4S
Molecular Weight	535.71 g/mol
Synonyms	DAPA; Dansyl-D-Arg-4-ethylpiperidine amide; Nα-(5-Dimethylaminonaphthalene-1-sulfonyl)-Nω-[(3-ethyl-1,5-pentanediyl)]-L-argininamide; 1-Dimethylaminonaphthalene-5-sulfonylarginine N-(3-ethyl-1,5-pentanediyl)amide; Dansyl-Arg-4-Ethylpiperidine Amide; Fluorogenic Protease Substrate DAPA; L-Argininamide, N2-[(5-(dimethylamino)-1-naphthalenyl)sulfonyl]-N5-(3-ethyl-1,5-pentanediyl)-
EINECS	Contact for details

Quality Control

Every batch of Dansylarginine n-(3-Ethyl-1,5-Pentanediyl)Amide is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and performance. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting key parameters such as assay (HPLC), related substances, and spectroscopic identification. Our quality commitment supports research requiring high reproducibility and reliable data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.