Description

Cefuroxime is a second-generation cephalosporin antibiotic belonging to the β-lactam class. It is valued for its broad-spectrum activity against a wide range of Gram-positive and Gram-negative bacteria, including β-lactamase-producing strains. This makes it a critical active pharmaceutical ingredient (API) for the formulation of injectable and oral antibiotic medications. Industries requiring this compound include pharmaceutical manufacturing, veterinary medicine, and advanced research in antimicrobial development.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of antibiotic formulations, including tablets, capsules, and sterile injectables.
• Veterinary Medicine: Used in the development of antibacterial treatments for livestock and companion animals.
• Research & Development: Serves as a reference standard and key intermediate in microbiological research and the development of new antibiotic derivatives.
• Hospital & Clinical Formulations: Essential for compounding pharmacies and manufacturers producing ready-to-use injectable solutions for hospital use.

Basic Information

Product Name	Cefuroxime
CAS No.	55268-75-2
Molecular Formula	C16H16N4O8S
Molecular Weight	424.39 g/mol
Synonyms	(6R,7R)-3-[(Carbamoyloxy)methyl]-7-[[(2Z)-2-furan-2-yl-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefuroxime Acid; Zinacef; Zinnat; Ceftin; (Z)-Isomer; Cefuroxime Axetil (prodrug form); FR 12363
EINECS	259-560-5

Quality Control

Our Cefuroxime is manufactured under strict quality management systems. It is typically supplied to meet or exceed relevant pharmacopeial standards such as USP, EP, and BP. Every batch undergoes comprehensive analytical testing including identification, assay, impurity profiling, and residual solvent analysis to ensure high purity and consistency. A Certificate of Analysis (COA) is provided with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Specific Optical Rotation	+63° to +70° (c=1, 0.1M HCl)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.