Description

Citalopram Related Compound F (200 Mg) (Dimethyl-(1-Methyl-3,3-Diphenyl-Allyl)-Amine Hydrochloride) is a high-purity chemical reference standard, specifically identified as a related compound of the antidepressant Citalopram. This compound is critical for pharmaceutical research and development, serving as a key impurity marker to ensure drug safety, efficacy, and regulatory compliance. It is primarily utilized by analytical laboratories, quality control departments, and R&D teams within the pharmaceutical and fine chemical industries for method development, validation, and routine testing.

Application

• Pharmaceutical Impurity Profiling and Control: Used as a certified reference standard for the identification and quantification of specific impurities in Citalopram Hydrobromide active pharmaceutical ingredient (API) and finished dosage forms.
• Analytical Method Development and Validation: Serves as a critical component in developing and validating High-Performance Liquid Chromatography (HPLC), Ultra-Performance Liquid Chromatography (UPLC), and other chromatographic methods for purity analysis.
• Quality Assurance/Quality Control (QA/QC): Essential for routine batch release testing in pharmaceutical manufacturing to monitor impurity levels against International Council for Harmonisation (ICH) guidelines.
• Regulatory Compliance and Documentation: Supports regulatory filings (e.g., for FDA, EMA) by providing definitive proof of impurity characterization and control strategies.
• Stability Studies: Employed as a marker compound in forced degradation and long-term stability studies of Citalopram to understand degradation pathways.
• Research and Development: Used in synthetic chemistry research to study the metabolism, pharmacokinetics, and degradation chemistry of Citalopram and related structures.

Basic Information

Product Name	Citalopram Related Compound F (200 Mg) (Dimethyl-(1-Methyl-3,3-Diphenyl-Allyl)-Amine Hydrochloride)
CAS No.	55011-89-7
Molecular Formula	C19H24ClN
Molecular Weight	301.85 g/mol
Synonyms	Dimethyl(1-methyl-3,3-diphenylallyl)amine hydrochloride; 1-Propanamine, N,N-dimethyl-3,3-diphenyl-2-methyl-, hydrochloride; Citalopram Impurity F; Citalopram Related Substance F; Citalopram EP Impurity F; Lu 10-171-F; N,N-Dimethyl-3,3-diphenyl-2-methylallylamine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Citalopram Related Compound F is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity, purity, and impurity profile testing using advanced analytical techniques to ensure compliance with pharmacopeial standards (e.g., USP, EP) and customer-specific requirements. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, related substances, residual solvents, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C (59-77°F). This product is hygroscopic (moisture-sensitive). The container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual unspecified impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.