Description

4-[(4-Fluorophenyl)Carbonyl]Benzonitrile is a high-purity aromatic nitrile derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a carbonyl and a nitrile group on a biphenyl core, makes it a versatile intermediate for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorinated aromatic system for enhanced bioactivity.
• Liquid Crystal & OLED Materials: Serves as a core building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to modify thermal stability, chemical resistance, and optical properties.
• Organic Synthesis Reagent: A valuable reagent in cross-coupling reactions, such as Suzuki and Sonogashira couplings, for constructing complex conjugated systems.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new synthetic pathways and novel compound libraries.

Basic Information

Product Name	4-[(4-Fluorophenyl)Carbonyl]Benzonitrile
CAS No.	54978-50-6
Molecular Formula	C14H8FNO
Molecular Weight	225.22 g/mol
Synonyms	4-(4-Fluorobenzoyl)benzonitrile; 4'-Fluoro-4-biphenylcarbonitrile; p-Fluorobenzophenone-4-carbonitrile; 4-Cyanophenyl 4-fluorophenyl ketone; [1,1'-Biphenyl]-4-carbonitrile, 4'-fluoro-; 4-Fluorobenzophenone-4'-carbonitrile; 4'-Fluorobenzophenone-4-carbonitrile; 4-(4-Fluorobenzoyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 4-[(4-Fluorophenyl)Carbonyl]Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	145 - 149 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.