Description

4-(Aminomethyl)Cyclohexane-1-Carbonitrile is a versatile bifunctional organic intermediate featuring both an amine and a nitrile group on a cyclohexane backbone. This unique structure makes it a valuable building block for synthesizing complex molecules in pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its cyclohexane scaffold for bioactive molecule design.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for specialty polymers, including polyamides and epoxy curing agents.
• Ligand and Catalyst Development: The aminomethyl and nitrile functionalities are useful for constructing chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Organic Synthesis Reagent: Employed in multi-step synthetic routes for the introduction of the cyclohexylamine moiety or for further functionalization of the nitrile group.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-(Aminomethyl)Cyclohexane-1-Carbonitrile
CAS No.	54898-73-6
Molecular Formula	C8H14N2
Molecular Weight	138.21 g/mol
Synonyms	4-(Aminomethyl)cyclohexanecarbonitrile; trans-4-(Aminomethyl)cyclohexanecarbonitrile; 4-Cyano-1-cyclohexanemethylamine; 1-Cyano-4-(aminomethyl)cyclohexane; 4-(Aminomethyl)-1-cyanocyclohexane; 4-Cyanocyclohexylmethylamine; (4-Cyanocyclohexyl)methanamine
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)Cyclohexane-1-Carbonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.