Description

n-Ethyl-n-(3-Carboxypropyl)Nitrosamine is a specialized nitrosamine compound of significant interest in research and analytical chemistry. This chemical serves as a critical reference standard and intermediate for the study of nitrosamine formation, analysis, and toxicology. It is primarily utilized by analytical laboratories, research institutions, and pharmaceutical development teams focused on impurity profiling and regulatory compliance. Its precise structure makes it an essential tool for method development and validation in sensitive detection assays.

Application

• Analytical Reference Standard: Primary use as a certified standard for the quantification and identification of nitrosamine impurities in pharmaceutical APIs, finished drug products, and consumer goods.
• Pharmaceutical Research: Employed in metabolism, mutagenicity, and carcinogenicity studies to understand the biological impact of nitrosamine exposure.
• Method Development & Validation: Critical for developing and validating sensitive analytical methods such as LC-MS/MS, GC-MS, and HPLC for trace-level nitrosamine analysis.
• Regulatory Compliance Testing: Used by quality control laboratories to ensure products comply with stringent global regulations (e.g., FDA, EMA, ICH M7) regarding nitrosamine limits.
• Chemical Synthesis Intermediate: Serves as a building block or precursor in organic synthesis for more complex nitrosamine derivatives in research settings.
• Environmental and Food Safety Analysis: Applied in trace analysis methods to detect nitrosamine contaminants in water, food, and agricultural products.

Basic Information

Product Name	n-Ethyl-n-(3-Carboxypropyl)Nitrosamine
CAS No.	54897-63-1
Molecular Formula	C7H14N2O3
Molecular Weight	174.20 g/mol
Synonyms	N-Ethyl-N-(3-carboxypropyl)nitrosamine; 4-(Ethylnitrosamino)butyric acid; N-Nitroso-N-ethyl-4-aminobutyric acid; N-Ethyl-N-nitrosoglycine butyric acid; N-Nitroso-N-ethyl-γ-aminobutyric acid; ECNA; N-Ethyl-N-(3-carboxypropyl)nitrous amide; N-Nitroso-N-ethyl-4-aminobutanoic acid
EINECS	Contact for details

Quality Control

Our n-Ethyl-n-(3-Carboxypropyl)Nitrosamine is produced and handled under strict quality management protocols. Each batch is subjected to rigorous identity confirmation, purity analysis, and impurity profiling using advanced analytical techniques to ensure it meets the high standards required for reference materials. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic data is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere if possible to maximize long-term stability. Store away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.