Description

Cytochalasing CAS NO 54874-57-6 is a potent fungal metabolite belonging to the cytochalasin family, known for its ability to disrupt actin polymerization in eukaryotic cells. This compound is a critical research tool for studying cell motility, morphology, and cytokinesis. It is primarily utilized by researchers in the fields of cell biology, pharmacology, and biochemistry for in vitro studies. Our supply ensures high purity and batch-to-batch consistency, supporting reliable and reproducible experimental outcomes.

Application

• Cell Biology Research: Used as a cytoskeletal disruptor to inhibit actin filament polymerization, facilitating studies on cell division, migration, and shape.
• Pharmacological Studies: Employed in research to investigate mechanisms of action for potential drug candidates affecting the cytoskeleton.
• Cancer Research: Applied in vitro to study the role of actin dynamics in tumor cell invasion, metastasis, and apoptosis.
• Developmental Biology: Utilized to examine the role of the actin cytoskeleton in embryogenesis and tissue differentiation processes.
• Neuroscience Research: Used to study synaptic vesicle trafficking and neuronal growth cone dynamics dependent on actin remodeling.
• Toxicology Screening: Serves as a reference or control compound in assays designed to identify toxins that target the cytoskeleton.

Basic Information

Product Name	Cytochalasing
CAS No.	54874-57-6
Molecular Formula	C29H37NO5
Molecular Weight	479.61 g/mol
Synonyms	Cytochalasin H; Cytochalasin H from Zygosporium masonii; NSC 209516; 7-Oxadehydrocytochalasin H; [1S-(1α,6β,7β,10α,11α,13α,14β,15E,18E)]-6,7-Epoxy-21,23-dihydroxy-1,10,14,18-tetramethyl-8-oxo-11-(1-oxopropyl)-4-azatricyclo[13.3.1.14,8]nonadeca-15,18-dien-13-yl acetate
EINECS	Contact for details

Quality Control

Our Cytochalasing is produced under strict quality management protocols to ensure it meets the exacting standards required for life science research. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and structural confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, purity, and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing desiccated under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.