Description

tert-Butyl (4-(Prop-2-Yn-1-Yloxy)Phenyl)Carbamate is a specialized organic building block featuring both a carbamate protecting group and an alkyne functional handle. This compound is valued for its dual reactivity, enabling its use as a key intermediate in sophisticated organic synthesis and pharmaceutical research. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and oncological pathways.
• Peptide Chemistry & PROTAC Development: The alkyne group enables efficient conjugation via click chemistry (e.g., CuAAC), making it valuable for synthesizing peptide derivatives, bioconjugates, and Proteolysis Targeting Chimeras (PROTACs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Acts as a monomer or cross-linker precursor in the development of advanced polymers, dendrimers, and functionalized surfaces.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological processes and target engagement.
• Academic & Contract Research: A key reagent in university and CRO laboratories for methodology development and exploring new synthetic routes.

Basic Information

Product Name	tert-Butyl (4-(Prop-2-Yn-1-Yloxy)Phenyl)Carbamate
CAS No.	54840-30-1
Molecular Formula	C14H17NO3
Molecular Weight	247.29 g/mol
Synonyms	Boc-4-(2-Propynyloxy)aniline; 4-(2-Propyn-1-yloxy)phenylcarbamic acid 1,1-dimethylethyl ester; tert-Butyl N-[4-(prop-2-yn-1-yloxy)phenyl]carbamate; 1,1-Dimethylethyl [4-(2-Propyn-1-yloxy)phenyl]carbamate; 4-(Prop-2-ynyloxy)phenylcarbamic Acid tert-Butyl Ester; Boc-4-Propargyloxyaniline; N-Boc-4-(propargyloxy)aniline; 4-(Propargyloxy)phenyl tert-butylcarbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl (4-(Prop-2-Yn-1-Yloxy)Phenyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.