Description

2-Fluoro-4-Methoxy-Dl-Phenylalanine is a fluorinated and methoxylated derivative of the amino acid phenylalanine, serving as a versatile non-natural amino acid building block. This compound is critical for medicinal chemistry research, enabling the synthesis of novel peptide-based therapeutics and bioactive molecules with enhanced metabolic stability and binding affinity. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and advanced material scientists seeking to incorporate unique steric and electronic properties into their molecular designs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, protease inhibitors, and peptide mimetics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to modulate the pharmacokinetic and pharmacodynamic profiles of lead compounds.
• Agrochemical Development: Serves as a precursor in creating novel herbicides or plant growth regulators with specific activity.
• Biochemical Tool: Employed in enzymatic studies to investigate substrate specificity and enzyme mechanisms.
• Peptide Synthesis: Incorporated into custom peptides to confer resistance to enzymatic degradation and alter physical properties.
• Material Science: Potential monomer for creating specialized polymers or coatings with unique characteristics.

Basic Information

Product Name	2-Fluoro-4-Methoxy-Dl-Phenylalanine
CAS No.	54788-29-3
Molecular Formula	C₁₀H₁₂FNO₃
Molecular Weight	213.21 g/mol
Synonyms	DL-2-Fluoro-4-methoxyphenylalanine; (RS)-2-Amino-3-(2-fluoro-4-methoxyphenyl)propanoic acid; 2-Fluoro-4-methoxy-DL-α-phenylalanine; 4-Methoxy-2-fluorophenylalanine; Fmoc-2-Fluoro-4-methoxy-DL-Phenylalanine (precursor); 2-F-4-MeO-DL-Phe; α-Amino-2-fluoro-4-methoxyhydrocinnamic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Methoxy-Dl-Phenylalanine is produced under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and development applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	DL-Racemate
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.