Description

(-)-Isoproterenol (+)-Bitartrate Salt is a high-purity enantiomer of the classic β-adrenergic receptor agonist. This specific salt form offers enhanced stability and solubility, making it a critical reference standard and active pharmaceutical ingredient (API) intermediate. It is essential for pharmaceutical R&D, analytical laboratories, and fine chemical synthesis requiring precise stereochemical control. Our supply ensures the quality and consistency demanded for advanced pharmacological studies and manufacturing.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification, assay, and impurity profiling of isoproterenol-based drug products in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key chiral building block in the synthesis of specialized cardiovascular and bronchial medications.
• Biochemical Research: Employed in pharmacological studies to investigate β-adrenergic receptor signaling pathways, mechanisms of action, and cardiac/ pulmonary effects.
• Analytical Method Development: Crucial for developing and validating chromatographic (HPLC, GC) and spectroscopic methods for drug analysis.
• Cell Culture & In Vitro Studies: Used in experimental models to study cellular responses to adrenergic stimulation.

Basic Information

Product Name	(-)-Isoproterenol (+)-Bitartrate Salt
CAS No.	54750-10-6
Molecular Formula	C11H17NO3 • C4H6O6
Molecular Weight	403.36 g/mol
Synonyms	(-)-Isoprenaline Bitartrate; (R)-(-)-Isoproterenol Bitartrate; L-Isoproterenol Bitartrate; L-Isoprenaline Bitartrate; 1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol (R)-(-)-enantiomer bitartrate salt; 4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol (R)-(-)-enantiomer bitartrate salt; Isoproterenol L-bitartrate; Norisodrine bitartrate
EINECS	Contact for details

Quality Control

Our (-)-Isoproterenol (+)-Bitartrate Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity assay, identification, and control of related substances, to ensure it meets exacting standards for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and in original packaging until use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Chiral Purity (Enantiomeric Excess)	≥99.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤1.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.