Description

Clonidine Related Compound A (25 Mg) (Acet-Ylclonidine) CAS NO 54707-71-0 is a high-purity analytical reference standard, specifically the acetamide derivative of clonidine. This compound is critical for quality control and research applications, serving as a key impurity marker to ensure the purity and safety of clonidine-based pharmaceutical products. It is primarily utilized by analytical laboratories, pharmaceutical R&D departments, and quality assurance teams in the manufacture of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Impurity Profiling and Control: Used as a certified reference material for the identification and quantification of related substances in clonidine hydrochloride API and finished dosage forms.
• Analytical Method Development and Validation: Serves as a critical standard for developing, calibrating, and validating HPLC, UPLC, and GC analytical methods in compliance with ICH guidelines.
• Pharmacological and Metabolic Research: Employed in studies investigating the metabolism, degradation pathways, and stability of clonidine and its structural analogs.
• Quality Assurance/Quality Control (QA/QC): Essential for routine batch testing in pharmaceutical manufacturing to meet stringent regulatory requirements from agencies like the FDA, EMA, and PMDA.
• Academic and Contract Research: Used in university and CRO settings for synthetic chemistry research, impurity synthesis, and teaching analytical techniques.

Basic Information

Product Name	Clonidine Related Compound A (Acet-Ylclonidine)
CAS No.	54707-71-0
Molecular Formula	C11H12Cl2N4O
Molecular Weight	287.15 g/mol
Synonyms	Acet-Ylclonidine; N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine, N-acetyl derivative; 2-[(2,6-Dichlorophenyl)amino]-4,5-dihydro-1H-imidazole-1-acetamide; Clonidine Impurity A; Clonidine EP Impurity A; Clonidine Related Substance A; STG-001; Acetylclonidine
EINECS	Contact for details

Quality Control

Every batch of Clonidine Related Compound A is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic techniques, to ensure compliance with pharmaceutical reference standard specifications. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, is provided with each unit and is available upon request.

Storage

Preserve in the original, tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.