Description

Hemoglobin-A0 CAS NO 54651-57-9 is a highly purified, native form of hemoglobin, the essential oxygen-transporting metalloprotein found in red blood cells. This product is critical for research and development in life sciences, providing a standardized and reliable reference material for biochemical studies. It is primarily utilized by pharmaceutical researchers, diagnostic kit manufacturers, and academic institutions investigating oxygen transport, blood substitutes, and hematological disorders.

Application

• Biochemical Research & Reference Standard: Used as a primary standard in spectrophotometric assays, enzyme studies, and investigations into protein structure-function relationships.
• Diagnostic Reagent Manufacturing: A key component in the calibration and production of in-vitro diagnostic (IVD) kits for clinical chemistry analyzers, particularly those measuring hemoglobin derivatives.
• Pharmaceutical Development: Serves as a critical raw material in R&D for blood substitute technologies and oxygen carrier therapeutics.
• Cell Culture & Hematology: Employed in specialized cell culture media and as a model compound in studies of erythrocyte function and hemolytic diseases.
• Educational & Teaching Tools: Used in university and professional laboratory settings to demonstrate principles of protein chemistry, ligand binding, and spectroscopy.

Basic Information

Product Name	Hemoglobin-A0
CAS No.	54651-57-9
Molecular Formula	C2952H4664N812O832S8Fe4
Molecular Weight	~64,500 Da (for α2β2 tetramer)
Synonyms	Hemoglobin A0; Human Hemoglobin A0; HbA0; Oxyhemoglobin A; Methemoglobin A (oxidized form); α-2-β-2 hemoglobin; Deoxyhemoglobin A (reduced form); CAS 54651-57-9
EINECS	Contact for details

Quality Control

Our Hemoglobin-A0 is produced and controlled under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including purity assessment by HPLC, spectrophotometric identity confirmation, and tests for relevant impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term stability, consider storage at -20°C under desiccant.

Specification

Item	Specification
Appearance	Dark red to brown lyophilized powder
Identification (IR / UV-Vis)	Conforms to standard
Purity (HPLC)	≥ 95% (HbA0)
Assay (Spectrophotometric)	≥ 95% of stated content
Methemoglobin Content	< 5%
Water Content (KF)	< 5%
Solubility	Soluble in water or buffer, clear solution
Biological Activity (O2 Binding)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.