Description

2-Bromo-n-(1-Hydroxy-2-Methylpropan-2-Yl)Benzamide is a specialized brominated benzamide derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a bromine substituent and a hindered hydroxyalkyl amide group, makes it a valuable building block for constructing complex molecules with specific steric and electronic properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those requiring brominated aromatic cores for further functionalization.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the benzamide scaffold is a common pharmacophore.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Chemistry: Employed in the creation of novel polymers or organic electronic materials that incorporate brominated aromatic units.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses serving the biotechnology and specialty chemical sectors.
• Academic and R&D Laboratories: Used in fundamental research exploring new organic reactions and methodologies involving halogenated amides.

Basic Information

Product Name	2-Bromo-n-(1-Hydroxy-2-Methylpropan-2-Yl)Benzamide
CAS No.	54596-21-3
Molecular Formula	C11H14BrNO2
Molecular Weight	272.14 g/mol
Synonyms	2-Bromo-N-(1-hydroxy-2-methylpropan-2-yl)benzamide; 2-Bromo-N-(2-hydroxy-1,1-dimethylethyl)benzamide; Benzamide, 2-bromo-N-(1-hydroxy-2-methyl-2-propanyl)-; 2-Bromobenzoic acid 1-hydroxy-2-methylpropan-2-ylamide; α-Bromo-N-(2-hydroxy-1,1-dimethylethyl)benzamide; BHB (abbreviation); CAS 54596-21-3
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-n-(1-Hydroxy-2-Methylpropan-2-Yl)Benzamide undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR, NMR), and impurity profile is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.