Description

Equinatoxin CAS NO 54578-46-0 is a potent pore-forming cytolysin and cardiotoxin isolated from the sea anemone *Actinia equina*. This high-purity, research-grade compound is a critical tool for studying membrane permeability, ion channel function, and cellular lysis mechanisms. It is primarily utilized by pharmaceutical researchers, toxicologists, and academic institutions in life science research, drug discovery programs, and the development of novel therapeutic agents.

Application

• Biomedical Research: Used as a model pore-forming agent to study cell membrane integrity, osmotic lysis, and the mechanics of protein insertion into lipid bilayers.
• Cardiotoxicity Studies: Employed in pharmacological and toxicological research to investigate its effects on cardiac muscle cells and ion channel function.
• Drug Discovery & Screening: Serves as a reference standard or tool compound in assays designed to identify potential inhibitors of cytolytic activity.
• Venom & Toxin Research: A key subject in comparative studies of marine toxins, their structure-activity relationships, and evolutionary biology.
• Membrane Biophysics: Essential for experiments probing lipid-protein interactions, vesicle permeabilization, and the formation of non-selective pores in synthetic membranes.
• Development of Bio-Tools: Potential use in designing targeted cytolytic agents for specific cell types in experimental settings.

Basic Information

Product Name	Equinatoxin
CAS No.	54578-46-0
Molecular Formula	C~H~N~O~S~ (Protein)
Molecular Weight	~19,500 Da (monomer)
Synonyms	Equinatoxin II; EqT II; ACTX-I; Sea Anemone Cytolysin; *Actinia equina* Toxin II; Pore-Forming Toxin from *Actinia equina*; EQT
EINECS	Contact for details

Quality Control

Our research-grade Equinatoxin is produced and purified under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot undergoes comprehensive analytical characterization, including assessment of purity, identity, and functional activity. A detailed Certificate of Analysis (COA) is provided, documenting specifications such as purity by HPLC, protein concentration, and biological potency. We adhere to ISO 9001 quality management principles in our manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to prevent repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure containers are sealed under anhydrous conditions after each use.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Protein Content (BCA)	≥ 90%
Biological Activity (Hemolytic Assay)	Specified per batch
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.