Description

1-Fluoro-4-[(Z)-2-Methoxyethenyl]Benzene is a specialized fluorinated aromatic building block featuring a methoxy-substituted ethenyl group in the Z-configuration. This compound is valued for its unique electronic and steric properties, making it a critical intermediate in advanced organic synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, including potential kinase inhibitors and CNS-active compounds.
• Agrochemical Research: Used in the development of novel herbicides and pesticides where the fluorine atom and specific alkene geometry enhance biological activity and stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and liquid crystals with tailored optical properties.
• Cross-Coupling Reactions: Acts as a substrate in Heck, Suzuki, and other palladium-catalyzed cross-coupling reactions to create complex biaryl and conjugated systems.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes due to its fluorophore-like structure.

Basic Information

Product Name	1-Fluoro-4-[(Z)-2-Methoxyethenyl]Benzene
CAS No.	54533-37-8
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	(Z)-1-Fluoro-4-(2-methoxyvinyl)benzene; (Z)-4-Fluoro-β-methoxystyrene; 1-Fluoro-4-[(1Z)-2-methoxyethenyl]benzene; (Z)-1-Methoxy-2-(4-fluorophenyl)ethene; 4-Fluoro-(Z)-β-methoxystyrene; Benzene, 1-fluoro-4-[(Z)-2-methoxyethenyl]-; (Z)-2-Methoxy-1-(4-fluorophenyl)ethene
EINECS	Contact for details

Quality Control

Our 1-Fluoro-4-[(Z)-2-Methoxyethenyl]Benzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to confirm identity, isomeric purity (Z-configuration), and chemical purity. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storage under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (Z-isomer, GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.