Description

3-Chloro-2-Methylbenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both chloro and methyl substituents on the benzonitrile core, makes it a valuable precursor for constructing complex molecules. This intermediate is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzonitrile moiety.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where its halogenated aromatic structure is integral to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals and polymers with specific electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Chloro-2-Methylbenzonitrile
CAS No.	54454-12-5
Molecular Formula	C8H6ClN
Molecular Weight	151.59 g/mol
Synonyms	2-Methyl-3-chlorobenzonitrile; 3-Chloro-o-tolunitrile; 2-Methyl-3-chlorobenzene carbonitrile; 3-Chloro-2-methylbenzenecarbonitrile; Benzonitrile, 3-chloro-2-methyl-; 3-Chloro-2-methyl-benzonitrile; 54454-12-5 (CAS)
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Methylbenzonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and GC-MS, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance records.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.