Description

Bz-Nle-Oh CAS NO 54430-46-5 is a protected amino acid derivative, specifically N-Benzoyl-L-norleucine, widely utilized as a crucial building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precision. It is primarily used by the pharmaceutical, biotechnology, and academic research sectors for drug discovery, development of therapeutic peptides, and biochemical studies.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of norleucine residues into peptide chains.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a linker or spacer molecule in the creation of peptide-protein or peptide-drug conjugates.
• Biochemical Tool Development: Employed in the synthesis of substrates, inhibitors, or standards for enzymatic assays and diagnostic applications.
• Academic & Industrial R&D: A fundamental reagent for exploring protein structure-function relationships and peptide chemistry.

Basic Information

Product Name	Bz-Nle-Oh
CAS No.	54430-46-5
Molecular Formula	C₁₃H₁₇NO₃
Molecular Weight	235.28 g/mol
Synonyms	N-Benzoyl-L-norleucine; (S)-2-Benzamidohexanoic acid; L-Norleucine, N-benzoyl-; Bz-Nle-OH; N-α-Benzoyl-L-norleucine; Benzoyl-norleucine; N-Benzoylnorleucine; Bz-L-Nle-OH
EINECS	Contact for details

Quality Control

Our Bz-Nle-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and cGMP applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Specific range available on COA
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.