Description

(Z)-n-(1,3-Dihydroxyoctadecan-2-Yl)Octadec-9-Enamide is a high-purity synthetic ceramide analog, a key structural component of the skin's lipid barrier. This compound matters for its critical role in advanced cosmetic and pharmaceutical formulations, where it enhances skin hydration, improves barrier function, and promotes cellular stability. Industries that need this specialized ingredient include premium skincare, dermatological research, and the development of high-performance lipid-based drug delivery systems.

Application

• Premium Skincare Formulations: Used as a primary active in anti-aging creams, serums, and moisturizers to restore and reinforce the skin's natural lipid barrier.
• Dermatological Preparations: Incorporated into therapeutic creams and ointments designed to treat conditions like eczema, psoriasis, and severe dryness.
• Lipid-Based Drug Delivery Systems: Serves as a structural lipid in nanocarriers (e.g., liposomes, niosomes) to improve the stability and skin penetration of active pharmaceutical ingredients.
• Hair Care Products: Added to conditioners and treatments to repair damaged hair cuticles and improve moisture retention.
• Cosmetic Research & Development: Employed as a reference standard and key ingredient in developing next-generation biomimetic cosmetic actives.
• Biomimetic Membrane Studies: Utilized in laboratory research to model and study the properties of biological membranes and lipid bilayers.

Basic Information

Product Name	(Z)-n-(1,3-Dihydroxyoctadecan-2-Yl)Octadec-9-Enamide
CAS No.	54422-45-6
Molecular Formula	C₃₆H₇₁NO₃
Molecular Weight	565.96 g/mol
Synonyms	N-(1,3-Dihydroxyoctadecan-2-yl)oleamide; Ceramide EOP; Ceramide EOS (C18); (2S,3R,4E)-2-N-[(9Z)-Octadecenoyl]-octadecasphinga-4,9-dienine-1,3-diol; Phytosphingosine-based ceramide; Oleoyl Phytosphingosine; Skin-identical ceramide; Synthetic Ceramide 3
EINECS	Contact for details

Quality Control

Our (Z)-n-(1,3-Dihydroxyoctadecan-2-Yl)Octadec-9-Enamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for cosmetic and pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC for assay and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 105 °C
Loss on Drying	≤ 1.0 %
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines
Microbial Limits	Meets USP <61> / Ph. Eur. 2.6.12

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.