Description

1-Chloro-5-Decyne is a versatile alkyne building block featuring a terminal chloro substituent, enabling diverse chemical transformations. This compound is valued for its role as a key intermediate in organic synthesis, particularly in the construction of more complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, leveraging the reactivity of both the alkyne and chloro functional groups.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the creation of specialized polymers, liquid crystals, and other advanced materials with tailored properties.
• Cross-Coupling Reactions: Acts as a substrate in Sonogashira, Heck, and other palladium-catalyzed coupling reactions to form carbon-carbon bonds.
• Organic Synthesis Building Block: Utilized for introducing the decyne moiety into larger molecules or for further functionalization to alcohols, amines, or other derivatives.
• Ligand and Catalyst Development: Provides a scaffold for creating novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	1-Chloro-5-Decyne
CAS No.	54377-34-3
Molecular Formula	C₁₀H₁₇Cl
Molecular Weight	172.70 g/mol
Synonyms	5-Decyn-1-yl chloride; 1-Chloro-5-decyne; 5-Decynyl chloride; Chlorodecyne; 10-Chloro-5-decyne; 1-Chlorodec-5-yne; n-Decyn-5-yl chloride
EINECS	Contact for details

Quality Control

Our 1-Chloro-5-Decyne is produced under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical properties is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.