Description

Flecainide Acetate CAS NO 54143-56-5 is the acetate salt form of flecainide, a class Ic antiarrhythmic agent. This high-purity pharmaceutical intermediate is critical for ensuring the efficacy and safety of the final drug product. It is primarily required by manufacturers in the pharmaceutical industry for the synthesis of finished dosage forms used to treat life-threatening ventricular arrhythmias.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: A key raw material in the synthesis of Flecainide Acetate as a finished API.
• Antiarrhythmic Drug Manufacturing: Used in the production of oral tablets and other formulations for treating ventricular tachycardia and fibrillation.
• Cardiac Research & Development: Serves as a reference standard and building block in preclinical and clinical research for cardiac electrophysiology.
• Generic Pharmaceutical Production: Essential for manufacturers developing bioequivalent versions of branded antiarrhythmic medications.
• Pharmaceutical Compounding: Used in specialized pharmacy settings for tailored patient medications where commercial formulations are unsuitable.

Basic Information

Product Name	Flecainide Acetate
CAS No.	54143-56-5
Molecular Formula	C17H20F6N2O3 • C2H4O2
Molecular Weight	474.39 g/mol
Synonyms	Flecainide Acetate Salt; N-(2-Piperidylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide acetate; (±)-Flecainide acetate; R-818 Acetate; Tambocor Acetate; Flecainide monoacetate; Benzamide, N-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)-, acetate (1:1)
EINECS	Contact for details

Quality Control

Our Flecainide Acetate is manufactured under strict quality systems suitable for pharmaceutical use. We provide material that meets or exceeds relevant pharmacopeial standards (e.g., USP, EP) for identity, purity, and strength. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, related substances, residual solvents, and other critical parameters to ensure compliance with your stringent requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.