Description

1,1,1-Trifluoro-4,4-Bis(Phenylthio)But-3-En-2-One is a specialized fluorinated organic building block featuring both trifluoromethyl and phenylthio functional groups. This compound is valued for its unique reactivity profile, serving as a key intermediate in the synthesis of complex molecules where the introduction of fluorine and sulfur moieties is critical. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and advanced materials sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for synthesizing specialty polymers and liquid crystals with tailored electronic or optical properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocycles and facilitating carbon-sulfur bond formation reactions.
• Fluorine Chemistry Studies: A valuable reagent for investigating new fluorination methodologies and the behavior of fluorinated enones in various reaction conditions.

Basic Information

Product Name	1,1,1-Trifluoro-4,4-Bis(Phenylthio)But-3-En-2-One
CAS No.	54083-61-3
Molecular Formula	C₁₈H₁₁F₃OS₂
Molecular Weight	364.40 g/mol
Synonyms	4,4-Bis(phenylthio)-1,1,1-trifluorobut-3-en-2-one; 1,1,1-Trifluoro-4,4-bis(phenylmercapto)-3-buten-2-one; 3-Buten-2-one, 1,1,1-trifluoro-4,4-bis(phenylthio)-; 54083-61-3; 4,4-Bis(phenylthio)-1,1,1-trifluoro-3-buten-2-one; TFBPB; Trifluoromethyl vinyl ketone phenyl sulfide derivative
EINECS	Contact for details

Quality Control

Our production of 1,1,1-Trifluoro-4,4-Bis(Phenylthio)But-3-En-2-One adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.