Description

D-Proline, 1-(Aminocarbonyl)- (9Ci) is a chiral, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in asymmetric synthesis, peptide mimetics, and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptidomimetics Research: Used in the design and synthesis of peptide analogs and mimetics to modulate biological activity and stability.
• Asymmetric Catalysis: Employed as a precursor or ligand component in the development of chiral catalysts for enantioselective reactions.
• Biochemical Research: Utilized as a specialized substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Fine Chemical Synthesis: Serves as a building block for the production of high-value specialty chemicals and agrochemicals.
• Academic & Industrial R&D: A valuable reagent for method development and exploration of new synthetic routes in organic chemistry.

Basic Information

Product Name	D-Proline, 1-(Aminocarbonyl)- (9Ci)
CAS No.	54080-03-4
Molecular Formula	C6H10N2O2
Molecular Weight	142.16 g/mol
Synonyms	1-Carbamoyl-D-proline; D-Prolinecarboxamide; (R)-1-Carbamoylpyrrolidine-2-carboxylic acid; (R)-Pyrolidine-2-carboxylic acid carboxamide; D-1-Carbamoylproline; (2R)-1-Carbamoyl-2-pyrrolidinecarboxylic acid; 54080-03-4; D-Proline, 1-carbamoyl-
EINECS	Contact for details

Quality Control

Our D-Proline, 1-(Aminocarbonyl)- (9Ci) is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the exacting standards required for pharmaceutical and advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.