Description

Propafenone is a class IC antiarrhythmic agent, a sodium channel blocker used to treat and prevent cardiac arrhythmias. Its primary value lies in its ability to stabilize the heart's electrical rhythm, making it a critical active pharmaceutical ingredient (API) for cardiovascular therapeutics. This compound is essential for pharmaceutical manufacturers developing and producing antiarrhythmic medications. Propafenone CAS NO 54063-53-5 is supplied in high-purity grades suitable for formulation into various dosage forms.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the manufacture of antiarrhythmic drugs.
• Formulation into oral solid dosage forms such as tablets and capsules for the treatment of ventricular arrhythmias.
• Research and development of new cardiovascular drug formulations and delivery systems.
• Used in clinical and preclinical studies to investigate cardiac electrophysiology.
• Reference standard in analytical laboratories for quality control and method validation.
• Potential use in combination therapies for complex cardiac conditions.

Basic Information

Product Name	Propafenone
CAS No.	54063-53-5
Molecular Formula	C21H27NO3
Molecular Weight	341.45 g/mol
Synonyms	Propafenone Hydrochloride (salt form); 2'-[2-Hydroxy-3-(propylamino)propoxy]-3-phenylpropiophenone; Rytmonorm; Rythmol; Fenopraine; SA-79; Baxarytmon; 1-[2-[2-Hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone
EINECS	Contact for details

Quality Control

Our Propafenone is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use, with specifications aligned with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing purity, identity, and impurity profiles to ensure supply reliability and regulatory compliance for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.