Description

Cefaclor is a second-generation cephalosporin antibiotic belonging to the β-lactam class. It is valued for its broad-spectrum activity against a wide range of Gram-positive and Gram-negative bacteria, making it a critical intermediate in pharmaceutical manufacturing. This compound is essential for producers of active pharmaceutical ingredients (APIs) and finished dosage forms targeting respiratory, urinary tract, and skin infections. Cefaclor CAS NO 53994-73-3 is supplied under stringent quality controls to ensure consistency and efficacy in final drug products.

Application

• Pharmaceutical API Synthesis: Primary use as an active pharmaceutical ingredient in the manufacture of oral antibiotic formulations.
• Generic Drug Production: Key raw material for manufacturers of generic cefaclor capsules, tablets, and oral suspensions.
• Veterinary Pharmaceuticals: Used in developing antibacterial treatments for companion and livestock animals.
• Clinical Research: Serves as a reference standard and building block in antimicrobial research and new drug development.
• Finished Dosage Forms: Incorporated into various solid and liquid dosage forms designed for systemic antibacterial therapy.

Basic Information

Product Name	Cefaclor
CAS No.	53994-73-3
Molecular Formula	C15H14ClN3O4S
Molecular Weight	367.81 g/mol
Synonyms	7-(D-2-Amino-2-phenylacetamido)-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; (6R,7R)-7-[[(2R)-2-Amino-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Ceclor; Alfatil; Distaclor; Panacef; Kefolor; Cefaclorum
EINECS	258-909-5

Quality Control

Our Cefaclor is manufactured and tested to meet high-purity standards suitable for pharmaceutical applications. Quality assurance protocols align with current Good Manufacturing Practices (cGMP). Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Specifications can be tailored to meet USP, EP, or other pharmacopeial standards upon request, ensuring compliance for global regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Specific Optical Rotation	+105° to +120°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.