Description

Diethylstilbestrol Bisglucuronide is a major, water-soluble metabolite of the synthetic estrogen diethylstilbestrol (DES). This compound is of significant importance in analytical and regulatory science for the detection and quantification of DES exposure. It serves as a critical reference standard for researchers and quality control laboratories in the pharmaceutical, veterinary, and food safety sectors, enabling precise monitoring and compliance testing.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for the calibration of analytical instruments and validation of testing methods.
• Metabolite Studies & Pharmacokinetics: Essential for research investigating the metabolism, distribution, and excretion profile of Diethylstilbestrol in biological systems.
• Veterinary Drug Residue Analysis: Used in the development and execution of LC-MS/MS and HPLC methods to detect illegal DES use in livestock and ensure food safety.
• Clinical Toxicology & Biomarker Assays: Employed in assays to monitor human exposure to DES, relevant for historical exposure studies and public health monitoring.
• Method Development & Validation: A key component for laboratories establishing or accrediting analytical procedures according to FDA, EMA, or other regulatory guidelines.
• Quality Control (QC) Testing: Used by manufacturers of testing kits and diagnostic assays to guarantee the accuracy and reliability of their products.

Basic Information

Product Name	Diethylstilbestrol Bisglucuronide
CAS No.	53915-13-2
Molecular Formula	C30H34O14
Molecular Weight	618.59 g/mol
Synonyms	DES Bisglucuronide; Diethylstilbestrol Diglucuronide; Diethylstilboestrol Bisglucuronide; Diethylstilbestrol Glucuronide (conjugate); 4,4'-(1,2-Diethyl-1,2-ethenediyl)bisphenol bis(β-D-glucopyranosiduronic acid); Stilbestrol Bisglucuronide; E,E-Diethylstilbestrol Bisglucuronide
EINECS	Contact for details

Quality Control

Our Diethylstilbestrol Bisglucuronide is manufactured and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for reference materials. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic data is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.