Description

4-Cyanobutanamide is a versatile nitrile-containing organic intermediate with significant synthetic utility. This compound is valued for its bifunctional reactivity, featuring both a cyano group and an amide moiety, which makes it a valuable building block for constructing more complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyrrolidinone or other nitrogen heterocycles.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require cyano-functionalized side chains.
• Polymer Chemistry: Serves as a monomer or co-monomer for specialty polymers, including polyamides and materials with specific thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in nucleophilic addition reactions, hydrolysis to dicarboxylic acid derivatives, and cyclization reactions to form lactams.
• Bioconjugation & Linker Chemistry: Utilized in the development of biochemical probes and antibody-drug conjugates (ADCs) where its functional groups allow for specific coupling strategies.
• Material Science Research: Investigated for creating novel organic frameworks and advanced materials with tailored electronic or optical characteristics.

Basic Information

Product Name	4-Cyanobutanamide
CAS No.	53897-27-1
Molecular Formula	C5H8N2O
Molecular Weight	112.13 g/mol
Synonyms	5-Oxopentanenitrile; Glutaramide nitrile; 4-Cyanobutyramide; 5-Cyanovaleramide; Pentanenitrile, 5-oxo-; Butanamide, 4-cyano-; 4-Cyano-butyramide; 5-Oxo-valeronitrile
EINECS	Contact for details

Quality Control

Our 4-Cyanobutanamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee supply reliability and product traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.