Description

Bamsa CAS NO 53892-58-3 is a specialized chemical intermediate, known in the industry as N,O-Bis(trimethylsilyl)acetamide. This compound is a powerful silylating agent, crucial for protecting reactive functional groups during complex synthetic sequences. It is an essential reagent for pharmaceutical manufacturers, agrochemical producers, and advanced material scientists who require high-purity intermediates for research, development, and production.

Application

• Pharmaceutical Synthesis: As a key silylating agent for protecting hydroxyl and amino groups in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the production of advanced pesticides and herbicides where selective protection of sensitive moieties is required.
• Analytical Chemistry: Employed in derivatization processes for gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) to enhance the volatility and detectability of polar compounds.
• Polymer & Material Science: Serves as a modifier or intermediate in the synthesis of specialty silicones and silicon-containing polymers.
• Peptide & Nucleotide Chemistry: Facilitates the protection of sensitive functional groups during solid-phase and solution-phase synthesis.
• Organic Synthesis R&D: A versatile reagent in academic and industrial research laboratories for constructing complex molecular architectures.

Basic Information

Product Name	Bamsa
CAS No.	53892-58-3
Molecular Formula	C8H21NOSi2
Molecular Weight	203.43 g/mol
Synonyms	N,O-Bis(trimethylsilyl)acetamide; BSA; Acetamide, N,O-bis(trimethylsilyl)-; Bis(trimethylsilyl)acetamide; N,O-Bis(trimethylsilyl)acetamide (BSA); 1,1,1-Trimethyl-N-(trimethylsilyl)silanamine, N-acetyl derivative; N-Acetyl-O-trimethylsilyl-N-trimethylsilylhydroxylamine
EINECS	258-848-7

Quality Control

Our Bamsa (53892-58-3) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by GC or titration and identity confirmation by IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can degrade the product. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.417 - 1.421
Density (g/mL, 20°C)	0.83 - 0.87

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.