Description

Benzyl 4-Iodobutylcarbamate is a versatile organic intermediate featuring both a reactive iodoalkyl chain and a carbamate protecting group. This compound is valued for its role in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a functionalized butyl linker.
• Peptidomimetic Synthesis: Used to introduce iodine-labeled or further functionalized side chains into peptide analogs and protease inhibitors.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Heck, Sonogashira, Suzuki) to form carbon-carbon bonds.
• Nucleoside/Nucleotide Chemistry: Intermediate for modifying nucleosides or creating novel nucleotide analogs with potential antiviral or anticancer activity.
• Polymer Functionalization: Employed to introduce reactive iodine sites or carbamate-protected amine functionalities into polymer backbones for advanced material science.
• Ligand and Catalyst Development: Useful precursor for synthesizing specialized ligands or organocatalysts containing iodine handles for further modification.

Basic Information

Product Name	Benzyl 4-Iodobutylcarbamate
CAS No.	53880-65-2
Molecular Formula	C12H16INO2
Molecular Weight	333.17 g/mol
Synonyms	Carbamic acid, N-(4-iodobutyl)-, phenylmethyl ester; Benzyl N-(4-iodobutyl)carbamate; 4-Iodo-N-(benzyloxycarbonyl)butylamine; N-Cbz-4-iodobutylamine; Cbz-4-iodobutylamine; (4-Iodobutyl)carbamic acid benzyl ester; N-(4-Iodobutyl)carbamic Acid Benzyl Ester; Z-4-Iodobutylamine
EINECS	Contact for details

Quality Control

Our Benzyl 4-Iodobutylcarbamate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. We ensure compliance with relevant industry standards for research-grade chemicals. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and specification adherence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in opaque secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.