Description

2-Cyclobutene-1-Carboxamide is a versatile and reactive chemical building block characterized by its strained cyclobutene ring and amide functionality. This compound is valued for its role as a key synthetic intermediate in the development of complex organic molecules and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for use in cycloaddition reactions and as a precursor for novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those with complex cyclic or constrained structures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive ring system.
• Organic Synthesis Building Block: A valuable reagent for [2+2] and other cycloaddition reactions to construct complex molecular frameworks in academic and industrial R&D.
• Material Science: Investigated as a monomer or cross-linking agent for the creation of polymers with unique thermal or mechanical properties.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	2-Cyclobutene-1-Carboxamide
CAS No.	53778-54-4
Molecular Formula	C5H7NO
Molecular Weight	97.12 g/mol
Synonyms	Cyclobut-2-ene-1-carboxamide; 2-Cyclobutene-1-carboxylic acid amide; 1-Carbamoylcyclobut-2-ene; 2-Cyclobutenecarboxamide; Cyclobut-2-enecarboxamide; 1-Aminocarbonyl-2-cyclobutene
EINECS	Contact for details

Quality Control

Our 2-Cyclobutene-1-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and protected from humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.