Description

4,4,4-Trifluoro-1-(3-Methylphenyl)-1,3-Butanedione is a specialized fluorinated diketone compound, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and aromatic ketone functionalities make it a valuable precursor for creating molecules with enhanced stability and specific electronic properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group improves lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for β-diketonate ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of fluorinated organic semiconductors and advanced polymers for electronic applications.
• Chemical Research & Development: A versatile fluorination building block for exploring new reaction pathways and creating novel chemical entities in academic and industrial R&D.

Basic Information

Item	Details
Product Name	4,4,4-Trifluoro-1-(3-Methylphenyl)-1,3-Butanedione
CAS No.	53764-99-1
Molecular Formula	C11H9F3O2
Molecular Weight	230.18 g/mol
Synonyms	1-(3-Methylphenyl)-4,4,4-trifluorobutane-1,3-dione; 3-Methylphenyl Trifluoroacetylacetone; 4,4,4-Trifluoro-1-(m-tolyl)-1,3-butanedione; m-Tolyl Trifluoroacetylacetone; 3-Methylbenzoyltrifluoroacetone; TFMBDA; TFMBA; 1,3-Butanedione, 4,4,4-trifluoro-1-(3-methylphenyl)-
EINECS	Contact for details

Quality Control

Our production of 4,4,4-Trifluoro-1-(3-Methylphenyl)-1,3-Butanedione adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released against comprehensive specifications, including identity confirmation by FT-IR and NMR, and purity determination by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.