Description

3-Bromo-2-Methylpropanenitrile is a versatile halogenated nitrile building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for applications such as nucleophilic substitution reactions and the synthesis of heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and resins.
• Organic Synthesis Building Block: Utilized in nucleophilic substitution (SN2) reactions to introduce the 3-bromo-2-methylpropyl moiety.
• Ligand and Catalyst Preparation: Employed in the synthesis of novel ligands for metal-catalyzed reactions.
• Chemical Research: A valuable reagent for method development and exploring new reaction pathways in academic and industrial laboratories.

Basic Information

Product Name	3-Bromo-2-Methylpropanenitrile
CAS No.	53744-77-7
Molecular Formula	C5H8BrN
Molecular Weight	162.03 g/mol
Synonyms	2-Methyl-3-bromopropanenitrile; (2-Bromo-1,1-dimethylethyl)cyanide; 3-Bromo-2-methylpropionitrile; 2-Bromo-2-methylpropionitrile (common misnomer); β-Bromoisobutyronitrile; Bromomethylpropionitrile; Isobutyronitrile, 3-bromo-
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Methylpropanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.