Description

2-Bromo-1-(3-Fluorophenyl)Ethan-1-One is a versatile and high-value fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its core value lies in its reactive bromoacetyl group and fluorinated aromatic ring, enabling precise molecular construction for complex target molecules. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology Probes: Employed in the development of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic & Institutional Research: Used in university and government laboratories for methodological development and exploratory chemistry projects.

Basic Information

Product Name	2-Bromo-1-(3-Fluorophenyl)Ethan-1-One
CAS No.	53631-18-8
Molecular Formula	C8H6BrFO
Molecular Weight	217.04 g/mol
Synonyms	3'-Fluoro-2-bromoacetophenone; 2-Bromo-3'-fluoroacetophenone; 1-(3-Fluorophenyl)-2-bromoethanone; 2-Bromo-1-(3-fluorophenyl)ethanone; α-Bromo-3-fluoroacetophenone; 3-Fluorophenacyl bromide; 3-Fluorophenyl bromomethyl ketone; 2-Bromo-3-fluorophenylethanone
EINECS	Contact for details

Quality Control

Our production of 2-Bromo-1-(3-Fluorophenyl)Ethan-1-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results. We operate under a quality system aligned with cGMP principles for API starting materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging. Store separately from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.