Description

12α-Hydroxy-5β-Androstane-3,17-Dione is a high-purity steroid derivative and a key intermediate in the synthesis of complex pharmaceutical compounds. Its specific stereochemistry makes it a valuable building block for research and development in medicinal chemistry. This compound is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on steroid-based drug discovery and metabolic pathway studies.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs) and therapeutic agents.
• Biochemical Research: Used as a reference standard or substrate in studies of steroid metabolism, enzyme activity (e.g., hydroxysteroid dehydrogenases), and hormone biosynthesis pathways.
• Fine Chemical Synthesis: Serves as a specialized starting material for the production of novel steroid analogs with potential biological activity.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) settings for investigative chemistry and drug discovery projects.
• Metabolite Standard: Can be used in analytical laboratories as a standard for the identification and quantification of related steroid metabolites in biological samples.

Basic Information

Product Name	12α-Hydroxy-5β-Androstane-3,17-Dione
CAS No.	53604-45-8
Molecular Formula	C19H28O3
Molecular Weight	304.43 g/mol
Synonyms	12α-Hydroxy-5β-androstane-3,17-dione; 5β-Androstane-12α-ol-3,17-dione; 12α-Hydroxyetiocholane-3,17-dione; 12α-Hydroxy-5β-etiocholane-3,17-dione; (5β,12α)-12-Hydroxyandrostane-3,17-dione; 12α-Hydroxy-5β-androstanedione
EINECS	Contact for details

Quality Control

Our 12α-Hydroxy-5β-Androstane-3,17-Dione is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) standards where applicable, ensuring the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.