Description

2',4'-Difluorobiphenyl-4-Acetic Acid is a high-purity fluorinated biphenyl derivative that serves as a critical advanced pharmaceutical intermediate (API intermediate). This compound is valued for its unique molecular structure, which is essential for synthesizing active pharmaceutical ingredients with specific biological activity profiles. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the stability imparted by the fluorine atoms.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with enhanced thermal and chemical stability.
• Organic Synthesis: Acts as a versatile fluorinated synthon in cross-coupling reactions and for introducing the biphenyl-acetic acid moiety into complex molecules.

Basic Information

Product Name	2',4'-Difluorobiphenyl-4-Acetic Acid
CAS No.	53591-80-3
Molecular Formula	C14H10F2O2
Molecular Weight	248.23 g/mol
Synonyms	4-(2,4-Difluorophenyl)benzenacetic Acid; [1,1'-Biphenyl]-4-acetic acid, 2',4'-difluoro-; 2',4'-Difluoro[1,1'-biphenyl]-4-acetic Acid; Difluorobiphenyl Acetic Acid; 2,4-DFBPA; 53591-80-3; 2',4'-Difluorobiphenylacetic Acid
EINECS	Contact for details

Quality Control

Our 2',4'-Difluorobiphenyl-4-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.