Description

L-Phenylalanine, n-[(1,1-Dimethylethoxy)Carbonyl]-, Ethyl Ester is a protected amino acid derivative, specifically a Boc-protected phenylalanine ethyl ester, which serves as a crucial chiral building block in organic synthesis. Its primary value lies in providing a versatile and reactive intermediate for the controlled synthesis of peptides and complex organic molecules, where the Boc group offers orthogonal protection. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries engaged in the development of active pharmaceutical ingredients (APIs), peptide-based therapeutics, and specialty biochemicals.

Application

• Peptide Synthesis: A key intermediate in solid-phase and solution-phase peptide synthesis for constructing peptide chains with specific sequences.
• Pharmaceutical Intermediates: Serves as a chiral precursor in the synthesis of various APIs and drug candidates, particularly those containing phenylalanine motifs.
• Bioconjugation & Linker Chemistry: Used in the preparation of modified peptides and protein conjugates for drug delivery systems and diagnostic applications.
• Fine Chemical Synthesis: Employed as a building block for the synthesis of non-peptidic compounds, flavors, fragrances, and advanced materials requiring chiral induction.
• Research & Development: A valuable reagent in academic and industrial R&D laboratories for exploring new synthetic methodologies and bioactive compounds.

Basic Information

Product Name	L-Phenylalanine, n-[(1,1-Dimethylethoxy)Carbonyl]-, Ethyl Ester
CAS No.	53588-99-1
Molecular Formula	C₁₆H₂₃NO₄
Molecular Weight	293.36 g/mol
Synonyms	Boc-L-Phenylalanine ethyl ester; N-Boc-L-Phenylalanine ethyl ester; Ethyl N-(tert-butoxycarbonyl)-L-phenylalaninate; (S)-Ethyl 2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate; Boc-Phe-OEt; N-α-Boc-L-phenylalanine ethyl ester; BOC-PHE-OET; L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our L-Phenylalanine, n-[(1,1-Dimethylethoxy)Carbonyl]-, Ethyl Ester is manufactured under strict quality management systems. We offer material suitable for research and commercial synthesis, with quality verified by modern analytical techniques including HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every batch to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent hydrolysis of the ester and protecting groups.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.