Description

Benzene, 5-Ethynyl-1,2,3-Trimethoxy- is a specialized aromatic compound featuring a unique ethynyl substituent on a trimethoxybenzene core, making it a valuable synthetic intermediate. This compound is critical for advanced organic synthesis, particularly in constructing complex molecular architectures for pharmaceuticals and materials science. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for its role as a key building block.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive scaffold.
• Material Science: Acts as a monomer or cross-linking agent in the production of advanced polymers and specialty resins with tailored properties.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags for bio-conjugation and imaging applications.
• Academic & Industrial R&D: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	Benzene, 5-Ethynyl-1,2,3-Trimethoxy-
CAS No.	53560-33-1
Molecular Formula	C11H12O3
Molecular Weight	192.21 g/mol
Synonyms	5-Ethynyl-1,2,3-trimethoxybenzene; 1,2,3-Trimethoxy-5-ethynylbenzene; 3,4,5-Trimethoxyphenylacetylene; 5-Ethynyl-1,2,3-trimethoxybenzene; 3,4,5-Trimethoxybenzeneacetylene; 3,4,5-Trimethoxyphenylethyne; 5-Ethynyl-1,2,3-trimethoxy-benzene
EINECS	Contact for details

Quality Control

Every batch of Benzene, 5-Ethynyl-1,2,3-Trimethoxy- undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.