Description

3-Trifluoromethylthiobenzamide is a specialized fluorinated benzamide derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the unique reactivity imparted by the trifluoromethylthio (-SCF3) group, a highly sought-after motif for modulating the physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients requiring enhanced metabolic stability and lipophilicity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the -SCF3 group can improve biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for developing functional materials, such as liquid crystals or organic semiconductors, due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the incorporation of fluorine and sulfur atoms into complex molecular architectures.

Basic Information

Product Name	3-Trifluoromethylthiobenzamide
CAS No.	53515-17-6
Molecular Formula	C8H6F3NOS
Molecular Weight	221.20 g/mol
Synonyms	3-(Trifluoromethylthio)benzamide; Benzamide, 3-[(trifluoromethyl)thio]-; m-(Trifluoromethylthio)benzamide; α,α,α-Trifluoro-m-toluenethioamide; 3-Trifluoromethylsulfanylbenzamide; 3-(Trifluoromethylsulfanyl)benzamide; 53515-17-6
EINECS	Contact for details

Quality Control

Our 3-Trifluoromethylthiobenzamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications for that specific lot. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.