Description

Cyclobutyl 2-Trifluoromethylphenyl Ketone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound is valued for its unique structural motif, which combines a cyclobutyl ring with a trifluoromethyl-substituted benzophenone core, enabling precise modulation of molecular properties. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the construction of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for creating molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of monomers or additives for specialty polymers with tailored optical or electronic properties.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags or molecular probes for biological imaging and diagnostic applications.

Basic Information

Product Name	Cyclobutyl 2-Trifluoromethylphenyl Ketone
CAS No.	53342-41-9
Molecular Formula	C12H11F3O
Molecular Weight	228.21 g/mol
Synonyms	2-Trifluoromethyl Cyclobutyl Phenyl Ketone; 1-Cyclobutyl-2'-(trifluoromethyl)acetophenone; (2-Trifluoromethylphenyl) Cyclobutyl Ketone; Cyclobutyl(o-trifluoromethylphenyl)methanone; 2'-Trifluoromethyl Cyclobutyl Phenyl Ketone; α-Cyclobutyl-2-(trifluoromethyl)acetophenone; Ketone, cyclobutyl 2-trifluoromethylphenyl
EINECS	Contact for details

Quality Control

Our Cyclobutyl 2-Trifluoromethylphenyl Ketone is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development from research quantities to commercial scale under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.