Description

Pentafluorophenyldifluorophosphine Sulfide is a specialized organophosphorus compound featuring a pentafluorophenyl group. This high-value intermediate is critical for the synthesis of advanced ligands and reagents used in catalysis and materials science. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorine-containing drug candidates.
• Catalyst & Ligand Precursor: Serves as a precursor for generating specialized phosphine sulfide ligands used in transition metal catalysis, including cross-coupling reactions.
• Agrochemical Synthesis: Employed in the research and development of next-generation fluorinated pesticides and herbicides.
• Materials Science Research: Used in the development of advanced polymeric materials and flame retardants due to its phosphorus-sulfur core.
• Chemical Vapor Deposition (CVD): Investigated as a potential precursor for depositing thin films containing phosphorus and sulfur.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the pentafluorophenyldifluorophosphinothioyl group into target molecules.

Basic Information

Product Name	Pentafluorophenyldifluorophosphine Sulfide
CAS No.	53327-21-2
Molecular Formula	C6F5PF2S
Molecular Weight	244.09 g/mol
Synonyms	Difluoro(pentafluorophenyl)phosphine sulfide; Pentafluorophenyldifluorothiophosphine; (Pentafluorophenyl)difluorophosphine sulfide; (Pentafluorophenyl)difluorothiophosphorane; Thiophosphoryl fluoride, (pentafluorophenyl)difluoro-; C6F5PF2S; Pentafluorophenyl difluorothiophosphate
EINECS	Contact for details

Quality Control

Every batch of Pentafluorophenyldifluorophosphine Sulfide is manufactured and tested under strict quality management protocols. We ensure product integrity through comprehensive analytical methods including NMR, GC-MS, and elemental analysis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and incompatible with strong bases; ensure the container is sealed under an inert atmosphere such as nitrogen or argon after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 95.0%
19F NMR Purity	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.