Description

3-Amino-2-Chlorobenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and a chloro substituent on the benzonitrile core, makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with heterocyclic structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging its reactive sites for molecular diversification.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing specialized azo dyes and high-performance pigments.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers due to its conjugated system.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions like Buchwald-Hartwig amination or Suzuki coupling for creating biaryl structures.
• Chemical Research & Development: Utilized as a standard or building block in medicinal chemistry and process optimization studies.

Basic Information

Product Name	3-Amino-2-Chlorobenzonitrile
CAS No.	53312-76-8
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	2-Chloro-3-aminobenzonitrile; 3-Amino-2-chlorobenzene carbonitrile; 2-Chloro-3-cyanoaniline; 1-Amino-2-chloro-3-cyanobenzene; Benzonitrile, 3-amino-2-chloro-; 3-Cyano-2-chloroaniline; (3-Amino-2-chlorophenyl) cyanide
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Chlorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.