Description

2-Hydroxy-4-Phenylbutyronitrile is a versatile chiral intermediate of significant importance in fine chemical synthesis. Its value lies in its utility as a key building block for the production of high-value pharmaceutical compounds and other specialty chemicals. This product is essential for manufacturers in the pharmaceutical, agrochemical, and advanced material sectors seeking reliable, high-purity intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of various active pharmaceutical ingredients (APIs), particularly in the development of cardiovascular and central nervous system drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, flavors, and fragrances.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to introduce chirality into target molecules.
• Research & Development: Utilized in academic and industrial R&D laboratories for exploring new synthetic routes and novel compound libraries.

Basic Information

Product Name	2-Hydroxy-4-Phenylbutyronitrile
CAS No.	53279-92-8
Molecular Formula	C10H11NO
Molecular Weight	161.20 g/mol
Synonyms	4-Phenyl-2-hydroxybutyronitrile; (RS)-2-Hydroxy-4-phenylbutyronitrile; (±)-2-Hydroxy-4-phenylbutanenitrile; 2-Hydroxy-4-phenylbutyric acid nitrile; 4-Phenyl-2-hydroxybutanenitrile; α-Hydroxy-γ-phenylbutyronitrile; DL-2-Hydroxy-4-phenylbutyronitrile
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-4-Phenylbutyronitrile is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical testing including HPLC, GC, and NMR. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.