Description

S-Adenosyl-3-Thiopropylamine is a specialized biochemical compound, a structural analog of S-adenosylmethionine (SAMe) where the methyl group is replaced by a thiopropylamine moiety. This modification makes it a valuable tool compound and intermediate in the research and development of enzyme inhibitors, particularly for methyltransferases involved in epigenetic regulation and other biological pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on drug discovery, biochemical assay development, and the study of cellular metabolism.

Application

• Biochemical Research: Serves as a key intermediate or reference standard in the study of S-adenosylmethionine-dependent methyltransferases.
• Enzyme Inhibition Studies: Used as a potential inhibitor or substrate analog to investigate the mechanism and kinetics of various methyltransferase enzymes.
• Pharmaceutical R&D: Acts as a building block or precursor in the synthesis of novel therapeutic agents targeting epigenetic pathways.
• Diagnostic Reagent Development: Employed in the formulation of assay kits for measuring methyltransferase activity or screening for modulators.
• Academic Research: Utilized in universities and research institutes for fundamental studies in biochemistry, molecular biology, and chemical biology.

Basic Information

Product Name	S-Adenosyl-3-Thiopropylamine
CAS No.	53186-57-5
Molecular Formula	C13H20N6O4S
Molecular Weight	356.40 g/mol
Synonyms	S-Adenosyl-L-homocysteamine; 5'-Deoxy-5'-(3-thiopropylamino)adenosine; 5'-S-(3-Aminopropyl)-5'-thioadenosine; Adenosyl-3-thiopropylamine; 3-Thiopropyl-S-adenosylamine; S-3-Aminopropylthioadenosine; Decarboxylated S-adenosylmethionine analog
EINECS	Contact for details

Quality Control

Our S-Adenosyl-3-Thiopropylamine is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing desiccated under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.