Description

2,6-Bis(Trifluoromethyl)Benzoyl Chloride is a highly reactive and versatile organofluorine building block. Its value lies in the unique electronic and steric properties imparted by the two trifluoromethyl groups, which are critical for modifying the biological activity and physical characteristics of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require a specialized precursor for synthesizing complex fluorinated compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance metabolic stability and lipophilicity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis, enabling novel synthetic pathways.
• Material Science: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials to improve thermal stability, chemical resistance, and optical properties.
• Custom Synthesis and R&D: A critical reagent for medicinal chemistry and process research in both academic and industrial laboratories exploring fluorochemistry.

Basic Information

Product Name	2,6-Bis(Trifluoromethyl)Benzoyl Chloride
CAS No.	53130-44-2
Molecular Formula	C9H3ClF6O
Molecular Weight	276.56 g/mol
Synonyms	2,6-Bis(trifluoromethyl)benzoyl chloride; α,α,α,α',α',α'-Hexafluoro-2,6-xyloyl chloride; 2,6-Di(trifluoromethyl)benzoyl chloride; Benzoyl chloride, 2,6-bis(trifluoromethyl)-; 2,6-Bis(trifluoromethyl)benzoic acid chloride
EINECS	Contact for details

Quality Control

Every batch of our 2,6-Bis(Trifluoromethyl)Benzoyl Chloride is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including assay and impurity profile by HPLC/GC, is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.