Description

2-Chloro-3-Oxopropanenitrile is a versatile and reactive organic building block, primarily valued for its α-chloro ketone and nitrile functionalities. This compound is essential for the synthesis of heterocyclic compounds and serves as a key intermediate in advanced pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development teams in the fine chemical, pharmaceutical, and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various active pharmaceutical ingredients (APIs), especially those containing pyrazole, isoxazole, and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its reactive sites allow for the introduction of specific bioactive moieties.
• Fine Chemical Building Block: Employed in organic synthesis for the preparation of complex molecules in research and development, including dyes, pigments, and functional materials.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial labs for methodology development and the exploration of new chemical reactions.

Basic Information

Product Name	2-Chloro-3-Oxopropanenitrile
CAS No.	53106-70-0
Molecular Formula	C3H2ClNO
Molecular Weight	103.51 g/mol
Synonyms	2-Chloro-3-oxopropionitrile; Chloroacetonitrile, formyl-; 3-Oxopropanenitrile, 2-chloro-; 2-Chloro-3-oxobutanenitrile (common misnomer); α-Chloro-β-oxopropionitrile; Formylchloroacetonitrile; Chloroacetyl cyanide; 2-Chloromalonaldehyde nitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Oxopropanenitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.