Description

2-(1,1,2,3,3,3-Hexafluoropropyl)Tetrahydrofuran is a specialized fluorinated heterocyclic compound that serves as a valuable building block in advanced chemical synthesis. Its unique structure, featuring a hexafluoropropyl side chain on a tetrahydrofuran ring, provides exceptional properties for demanding applications. This high-value intermediate is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel molecules with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing fluorine atoms to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorinated moiety can improve efficacy and environmental profile.
• Advanced Material Precursor: Serves as a monomer or modifier in the synthesis of specialty polymers, coatings, and liquid crystals, imparting properties like chemical resistance, low surface energy, and thermal stability.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecular architectures, leveraging its reactivity for ring-opening or functional group transformations.
• Electrolyte Additive Research: Investigated for use in lithium-ion battery electrolytes to enhance stability and performance at high voltages.

Basic Information

Item	Details
Product Name	2-(1,1,2,3,3,3-Hexafluoropropyl)Tetrahydrofuran
CAS No.	53005-42-8
Molecular Formula	C7H8F6O
Molecular Weight	222.13 g/mol
Synonyms	2-(1,1,2,3,3,3-Hexafluoropropyl)oxolane; 2-(Perfluoropropyl)tetrahydrofuran; 2-(1,1,2,3,3,3-Hexafluoropropyl)THF; Tetrahydro-2-(1,1,2,3,3,3-hexafluoropropyl)furan; 2-(Hexafluoropropyl)tetrahydrofuran; Oxolane, 2-(1,1,2,3,3,3-hexafluoropropyl)-; 1,1,2,3,3,3-Hexafluoro-1-(tetrahydro-2-furanyl)-1-propane
EINECS	Contact for details

Quality Control

Every batch of 2-(1,1,2,3,3,3-Hexafluoropropyl)Tetrahydrofuran is produced and analyzed under a strict quality management system to ensure consistency and reliability for your critical processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat sources and open flame. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.