Description

4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid is a high-purity, functionalized stilbene derivative of significant importance in biochemical and pharmaceutical research. This compound serves as a critical bifunctional crosslinking agent, enabling the study of protein structure and interactions. It is primarily sought by research institutions, diagnostic kit manufacturers, and pharmaceutical development laboratories engaged in advanced proteomics and assay development.

Application

• Biochemical Crosslinking Agent: Used for studying protein-protein interactions and conformational changes in structural biology.
• Fluorescent Probe Synthesis: Acts as a key intermediate in the preparation of fluorescent dyes and labels for bioimaging and flow cytometry.
• Diagnostic Reagent Manufacturing: Employed in the development of enzyme-linked immunosorbent assay (ELISA) kits and other immunoassay components.
• Pharmaceutical Research: Utilized in drug discovery for target identification and the study of ligand-receptor binding mechanisms.
• Material Science: Investigated for the synthesis of functional polymers and advanced materials with specific optical properties.

Basic Information

Product Name	4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid
CAS No.	53005-05-3
Molecular Formula	C₁₆H₁₀N₂O₆S₄
Molecular Weight	454.52 g/mol
Synonyms	DIDS; 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic Acid; DIDS Acid; Stilbene-2,2'-disulfonic acid, 4,4'-diisothiocyanato-; 4,4'-Diisothiocyanatodihydrostilbene-2,2'-disulfonic Acid; H₂DIDS (reduced form); NSC 76816
EINECS	Contact for details

Quality Control

Our 4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and diagnostic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.