Description

2-Bromo-4-Chlorophenylacetonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and chlorine substituents, makes it a valuable precursor for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This intermediate is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used as a building block for developing advanced herbicides, fungicides, and insecticides, leveraging its halogenated phenyl ring for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers where specific halogenated aromatic units are required.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-4-Chlorophenylacetonitrile
CAS No.	52864-54-7
Molecular Formula	C8H5BrClN
Molecular Weight	230.49 g/mol
Synonyms	(2-Bromo-4-chlorophenyl)acetonitrile; 2-Bromo-4-chlorobenzyl cyanide; α-Bromo-4-chlorophenylacetonitrile; 4-Chloro-2-bromophenylacetonitrile; 2-Bromo-4-chlorobenzeneacetonitrile; (2-Bromo-4-chlorophenyl)ethanenitrile; Benzeneacetonitrile, 2-bromo-4-chloro-
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chlorophenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.